Maisto papildas nėščiosioms Aliness Prenacare FOLIAN 800 µg folio rūgšties, 60 tablečių

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Prekė: Maisto papildas nėščiosioms Aliness Prenacare FOLIAN 800 µg folio rūgšties, 60 tablečių. Kategorija: Vitaminų ir mineralų papildai.

• Gamintojas: Aliness
• Modelis: 5903242583186

DIETARY SUPPLEMENT ALINESS

FOLIAN 800 µg Folic acid

60 VEGE tablets

For pregnant women / Pregnancy / Fatigue

✅ contributes to the growth of maternal tissues during pregnancy,

✅ helps in proper blood production,

✅ helps maintain proper psychological functions,

✅ improves memory and concentration, especially can be helpful for the elderly,

✅ helps maintain normal metabolism of homocysteine,

✅ contributes to reduction of tiredness and fatigue,

✅ helps in the proper functioning of the immune system.

O PRODUCT

➡ BENEFITS OF SUPPLEMENTATION:

Pregnancy/ lactation:

• Increased demand for folate occurs during very active growth of body cells, such as during pregnancy and lactation.
• Quatrefolic® as a source of (6S)-5-methyltetrahydrofolate (5-MTHF) may be particularly useful in providing a nutritionally active form of folate in the period before conception, during pregnancy and lactation.
• Folate concentrations in breast milk are maintained at the expense of its reserves in the mother's body.
• A nursing woman needs 128 μg per day of additional folate to supplement her consumption.
• 5-MTHF has been shown to be effective and perhaps more effective than folic acid in maintaining folate concentrations in erythrocytes during lactation.

Infants and children:

• Folate is a critical nutrient when the growth of cells in the body is very active. It helps in the proper functioning of the immune system.

Adults:

• Folate is involved in the production of key neurotransmitters in the brain, helping to maintain normal psychological functions.
• Folate is a cofactor in many important biological reactions, and its deficiency can occur at all stages of life.
• Folate supplementation can improve quality of life by reduce fatigue and fatigue

Older people:

• Folin deficiency occurs in approx. 30% of the older population.
• Folate supplementation is important in older people because with age, the level of homocysteine in the blood rises and its metabolism depends on folate.
• As part of the aging process, numerous physical and physiological changes occur.
• Aging is associated with changes in the functioning of the gastrointestinal tract, which may possibly affect the absorption of various forms of folate. Supplementation of folate with high bioavailability, especially in this age group, allows to support correct psychological functions such as concentration, memory and learning.

Folates are susceptible to oxidation, rapidly lose activity in food and are largely, up to 90%, destroyed by cooking.

Quatrefolic, a highly bioavailable form of folate, may be the best choice when it comes to supplementing with active folate to support and regulate the methylation cycle.

The biotransformation of folic acid to 5-MTHF in the liver is regulated by two polymorphic enzymes, DHFR and MTHFR. DHFR activity appears to be low and highly variable. Chronic exposure of the liver to folic acid can cause saturation with this component, which can cause systemic circulation of unmetabolized folic acid. In addition, some people experience genetic changes that reduce DHFR activity.

A new study published in 2014 clearly indicated that 86% of the folic acid in the hepatic portal vein is unmetabolized, with almost all of the natural folate being converted correctly.

➡ Quaterfolic - BIOAVAILABILITY

Quatrefolic® passes through the gastric barrier and is absorbed mainly in the small intestine through the carrier mechanism.

The oral bioavailability of the active ingredient is highly dependent on its solubility. Absorption of the compound occurs after dispersion and dissolution in the fluid in the intestines.

➡ What does solubility mean?

High water solubility means that Quatrefolic® can be easily absorbed by mucosal cells that facilitate access to blood and circulation, with the possibility of improving the bioavailability of this chemical form of folate.

The extremely high solubility of Quatrefolic® in water is due to two specific characteristics of the component: the glucosamine-forming agent and the amorphous chemical structure of the product

The amorphous state provides inseparably related solubility, guaranteeing a homogeneous and reproducible dissolution process, while the crystalline alternative cannot provide this.

➡ Quaterfolic - STABILITY

Quatrefolic exhibits extraordinary, long-term chemical stability guaranteeing completely unchanged purity even after a few months, and reduction from analysis within 18 months lower than 1%, which allows easy application and storage. The pH value of Quatrefolic after reconstitution is neutral. This value also provides higher stability to the molecule, protecting it from hydrolytic degradation.

The stability of Quatrefolic powder was tested in accordance with the ICH guidelines (International Council for the Harmonisation of Technical Requirements for the Registration of Medicinal Products for Human Use) both at room temperature and under other storage conditions for samples in airtight containers protecting against light, and with the measurement of purity and result at different points.

Medicaline has deliberately decided to conduct stability studies Quatrefolic in accordance with the strictest guidelines, required specifically for pharmaceutical ingredients, guaranteeing independent and reliable criteria in order to make a statement of long-term chemical stability before starting the promotion of the product to its customers.

The lyophilised component can be used without special and restrictive conditions, easily combined with other ingredients and reagents, and can be stored at room temperature instead of at 2 to 8°C, like other folate derivatives.

INGREDIENTS

Bulking agent: microcrystalline cellulose, glucosamine salt of Quatrefolic® acid (6S)-5-methyltetrahydropholic acid.

Daily portion - (1 tablet) contains:

• Glucosamine salt of (6S)-5-methyltetrahydropholic acid - 1441 µg,

• including folate - 800 µg (400%).

RWS (%) - daily reference intake.

DOSAGE

Recommended daily dose: 1 tablet.

Package contents: 60 VEGE tablets.

ADDITIONAL INFORMATION

Precautions: Do not exceed the recommended daily dose. The product cannot be used as a substitute (replacement) for a varied diet. It is recommended to follow a balanced diet and a healthy lifestyle. Store at room temperature out of reach of small children. Protect from moisture.

Producer

MedicaLine

Ostrówiec 150

05-480 Karczew

ABOUT THE BRAND

The Aliness brand has been developing advanced production technologies for many years. It is a Polish company based on Polish capital. As a few in this industry, they have a modern production plant and development and research facilities, which are located in Karczew near Warsaw.

Aliness meets the highest European Production and Warehousing Standardsa based on the GMP and HACCP pharmaceutical standards. They have their own production, modern plant and warehouse of raw materials and finished products, their own development department and staff of experienced technologists and production specialists, which enables them to react quickly to the needs of consumers and maintain high quality standards and repeatability of manufactured products.

Specifications

Group	Name	Value
Parametry	Condition	new
Parametry	Invoice	With VAT invoice
Parametry	Manufacturer code	5903242583186
Parametry	Medical device	no
Parametry	Brand	Aliness
Parametry	Name	Folian 800
Parametry	For	for pregnant women
Parametry	Form	tablets
Parametry	Number of pieces	60 pcs
Parametry	Basic ingredient	folic acid
Parametry	Product weight with unit packaging	0.04 kg
Parametry	EAN (GTIN)	5903242583186
Parametry	Packaging status	original
Parametry	Additional features	gluten-free,lactose-free,safe for pregnant women,pure (without additives),vegan,vegetarian