{"product_id":"maisto-papildas-nesciosioms-aliness-prenacare-folian-800-g-folio-rugsties-60-tableciu","title":"Maisto papildas nėščiosioms Aliness Prenacare FOLIAN 800 µg folio rūgšties, 60 tablečių","description":"\u003ch2\u003eTrumpai apie prekę\u003c\/h2\u003e\u003cp\u003ePrekė: Maisto papildas nėščiosioms Aliness Prenacare FOLIAN 800 µg folio rūgšties, 60 tablečių. Kategorija: Vitaminų ir mineralų papildai.\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eGamintojas:\u003c\/strong\u003e Aliness\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eModelis:\u003c\/strong\u003e 5903242583186\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eDIETARY SUPPLEMENT ALINESS\u003c\/h2\u003e \u003ch2\u003eFOLIAN 800 µg Folic acid\u003c\/h2\u003e \u003ch2\u003e60 VEGE tablets\u003c\/h2\u003e \u003ch2\u003eFor pregnant women \/ Pregnancy \/ Fatigue\u003c\/h2\u003e \u003cp\u003e✅ contributes to the growth of \u003cb\u003ematernal tissues during pregnancy,\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e✅ helps in \u003cb\u003eproper blood production\u003c\/b\u003e,\u003c\/p\u003e \u003cp\u003e✅ helps maintain proper \u003cb\u003epsychological functions,\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e✅ \u003cb\u003eimproves memory and concentration\u003c\/b\u003e, especially can be helpful for the elderly,\u003c\/p\u003e \u003cp\u003e✅ helps maintain normal \u003cb\u003emetabolism of homocysteine\u003c\/b\u003e,\u003c\/p\u003e \u003cp\u003e✅ contributes to \u003cb\u003ereduction of tiredness and fatigue\u003c\/b\u003e,\u003c\/p\u003e \u003cp\u003e✅ helps in the proper \u003cb\u003efunctioning of the immune system\u003c\/b\u003e.\u003c\/p\u003e\u003ch2\u003eO PRODUCT\u003c\/h2\u003e \u003cp\u003e\u003cb\u003e➡ \u003c\/b\u003e\u003cb\u003eBENEFITS OF SUPPLEMENTATION:\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePregnancy\/ lactation:\u003c\/b\u003e\u003c\/p\u003e \u003cul\u003e \u003cli\u003eIncreased demand for folate occurs during very active growth of body cells, such as during pregnancy and lactation.\u003c\/li\u003e \u003cli\u003eQuatrefolic® as a source of (6S)-5-methyltetrahydrofolate (5-MTHF) may be particularly useful in providing a nutritionally active form of folate in the period before conception, during pregnancy and lactation.\u003c\/li\u003e \u003cli\u003eFolate concentrations in breast milk are maintained at the expense of its reserves in the mother's body.\u003c\/li\u003e \u003cli\u003e\u003cb\u003eA nursing woman needs 128 μg per day of additional folate to supplement her consumption.\u003c\/b\u003e\u003c\/li\u003e \u003cli\u003e5-MTHF has been shown to be effective and perhaps more effective than folic acid in maintaining folate concentrations in erythrocytes during lactation.\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003e\u003cb\u003eInfants and children:\u003c\/b\u003e\u003c\/p\u003e \u003cul\u003e \u003cli\u003eFolate is a critical nutrient when the growth of cells in the body is very active. It helps in the \u003cb\u003eproper functioning of the immune system\u003c\/b\u003e.\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003e\u003cb\u003eAdults:\u003c\/b\u003e\u003c\/p\u003e \u003cul\u003e \u003cli\u003eFolate is involved in the production of key neurotransmitters in the brain, helping to maintain normal psychological functions.\u003c\/li\u003e \u003cli\u003eFolate is a cofactor in many important biological reactions, and its deficiency can occur at all stages of life.\u003c\/li\u003e \u003cli\u003eFolate supplementation can improve quality of life by \u003cb\u003ereduce fatigue and fatigue\u003c\/b\u003e\n\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003e\u003cb\u003eOlder people:\u003c\/b\u003e\u003c\/p\u003e \u003cul\u003e \u003cli\u003e\n\u003cb\u003eFolin deficiency occurs in approx.\u003c\/b\u003e \u003cb\u003e30% of the older population.\u003c\/b\u003e\n\u003c\/li\u003e \u003cli\u003eFolate supplementation is important in older people because with age, the level of homocysteine in the blood rises and its metabolism depends on folate.\u003c\/li\u003e \u003cli\u003eAs part of the aging process, numerous physical and physiological changes occur.\u003c\/li\u003e \u003cli\u003eAging is associated with changes in the functioning of the gastrointestinal tract, which may possibly affect the absorption of various forms of folate. Supplementation of folate with high bioavailability, especially in this age group, allows to support \u003cb\u003ecorrect psychological functions such as concentration, memory and learning\u003c\/b\u003e.\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003eFolates are susceptible to oxidation, rapidly lose activity in food and are largely, up to 90%, destroyed by cooking.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eQuatrefolic\u003c\/b\u003e, a highly bioavailable form of folate, may be the best choice when it comes to supplementing with active folate to support and regulate the methylation cycle.\u003c\/p\u003e \u003cp\u003eThe biotransformation of folic acid to 5-MTHF in the liver is regulated by two polymorphic enzymes, DHFR and MTHFR. DHFR activity appears to be low and highly variable. Chronic exposure of the liver to folic acid can cause saturation with this component, which can cause systemic circulation of unmetabolized folic acid. In addition, some people experience genetic changes that reduce DHFR activity.\u003c\/p\u003e \u003cp\u003eA new study published in 2014 clearly indicated that 86% of the folic acid in the hepatic portal vein is unmetabolized, with almost all of the natural folate being converted correctly.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e➡ Quaterfolic - BIOAVAILABILITY\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003eQuatrefolic®\u003c\/b\u003e passes through the gastric barrier and is absorbed mainly in the small intestine through the carrier mechanism.\u003c\/p\u003e \u003cp\u003eThe oral bioavailability of the active ingredient is highly dependent on its solubility. Absorption of the compound occurs after dispersion and dissolution in the fluid in the intestines.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e➡ What does solubility mean?\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eHigh water solubility means that \u003cb\u003eQuatrefolic®\u003c\/b\u003e can be easily absorbed by mucosal cells that facilitate access to blood and circulation, with the possibility of improving the bioavailability of this chemical form of folate.\u003c\/p\u003e \u003cp\u003eThe extremely high solubility of \u003cb\u003eQuatrefolic®\u003c\/b\u003e in water is due to two specific characteristics of the component: the glucosamine-forming agent and the amorphous chemical structure of the product\u003c\/p\u003e \u003cp\u003eThe amorphous state provides inseparably related solubility, guaranteeing a homogeneous and reproducible dissolution process, while the crystalline alternative cannot provide this.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e➡ Quaterfolic - STABILITY\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003eQuatrefolic\u003c\/b\u003e exhibits extraordinary, long-term chemical stability guaranteeing completely unchanged purity even after a few months, and reduction from analysis within 18 months lower than 1%, which allows easy application and storage. The pH value of Quatrefolic after reconstitution is neutral. This value also provides higher stability to the molecule, protecting it from hydrolytic degradation.\u003c\/p\u003e \u003cp\u003eThe stability of \u003cb\u003eQuatrefolic\u003c\/b\u003e powder was tested in accordance with the ICH guidelines (International Council for the Harmonisation of Technical Requirements for the Registration of Medicinal Products for Human Use) both at room temperature and under other storage conditions for samples in airtight containers protecting against light, and with the measurement of purity and result at different points.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eMedicaline has deliberately decided to conduct stability studies\u003c\/b\u003e \u003cb\u003eQuatrefolic\u003c\/b\u003e in accordance with the strictest guidelines, required specifically for pharmaceutical ingredients, guaranteeing independent and reliable criteria in order to make a statement of long-term chemical stability before starting the promotion of the product to its customers.\u003c\/p\u003e \u003cp\u003eThe lyophilised component can be used without special and restrictive conditions, easily combined with other ingredients and reagents, and can be stored at room temperature instead of at 2 to 8°C, like other folate derivatives.\u003c\/p\u003e \u003cp\u003e\u003c\/p\u003e\u003ch2\u003eINGREDIENTS\u003c\/h2\u003e \u003cp\u003eBulking agent: microcrystalline cellulose, glucosamine salt of Quatrefolic® acid (6S)-5-methyltetrahydropholic acid.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eDaily portion - (1 tablet\u003c\/b\u003e\u003cb\u003e) contains:\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e• Glucosamine salt of (6S)-5-methyltetrahydropholic acid - 1441 µg,\u003c\/p\u003e \u003cp\u003e• including folate - 800 µg (400%).\u003c\/p\u003e \u003cp\u003e\u003cb\u003eRWS (%) - \u003c\/b\u003edaily reference intake.\u003c\/p\u003e \u003ch2\u003eDOSAGE\u003c\/h2\u003e \u003cp\u003e\u003cb\u003eRecommended daily dose\u003c\/b\u003e: 1 tablet.\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePackage contents: \u003c\/b\u003e60 VEGE tablets.\u003c\/p\u003e\u003ch2\u003eADDITIONAL INFORMATION\u003c\/h2\u003e\u003cp\u003e\u003cb\u003ePrecautions:\u003c\/b\u003e Do not exceed the recommended daily dose. The product cannot be used as a substitute (replacement) for a varied diet. It is recommended to follow a balanced diet and a healthy lifestyle. Store at room temperature out of reach of small children. Protect from moisture.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProducer\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eMedicaLine\u003c\/p\u003e\u003cp\u003eOstrówiec 150\u003c\/p\u003e\u003cp\u003e05-480 Karczew\u003c\/p\u003e\u003ch2\u003eABOUT THE BRAND\u003c\/h2\u003e\u003cp\u003eThe Aliness brand has been developing advanced production technologies for many years. It is a \u003cb\u003ePolish company based on Polish capital\u003c\/b\u003e. As a few in this industry, they have a modern production plant and development and research facilities, which are located in Karczew near Warsaw.\u003c\/p\u003e\u003cp\u003eAliness \u003cb\u003emeets the highest European Production and Warehousing Standards\u003c\/b\u003ea based on the GMP and HACCP pharmaceutical standards. They have their own production, modern plant and warehouse of raw materials and finished products, their own development department and staff of experienced technologists and production specialists, which enables them to react quickly to the needs of consumers and maintain high quality standards and repeatability of manufactured products.\u003c\/p\u003e\u003ch2\u003eSpecifications\u003c\/h2\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eGroup\u003c\/th\u003e\n\u003cth\u003eName\u003c\/th\u003e\n\u003cth\u003eValue\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eParametry\u003c\/td\u003e\n\u003ctd\u003eCondition\u003c\/td\u003e\n\u003ctd\u003enew\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eParametry\u003c\/td\u003e\n\u003ctd\u003eInvoice\u003c\/td\u003e\n\u003ctd\u003eWith VAT invoice\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eParametry\u003c\/td\u003e\n\u003ctd\u003eManufacturer code\u003c\/td\u003e\n\u003ctd\u003e5903242583186\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eParametry\u003c\/td\u003e\n\u003ctd\u003eMedical device\u003c\/td\u003e\n\u003ctd\u003eno\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eParametry\u003c\/td\u003e\n\u003ctd\u003eBrand\u003c\/td\u003e\n\u003ctd\u003eAliness\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eParametry\u003c\/td\u003e\n\u003ctd\u003eName\u003c\/td\u003e\n\u003ctd\u003eFolian 800\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eParametry\u003c\/td\u003e\n\u003ctd\u003eFor\u003c\/td\u003e\n\u003ctd\u003efor pregnant women\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eParametry\u003c\/td\u003e\n\u003ctd\u003eForm\u003c\/td\u003e\n\u003ctd\u003etablets\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eParametry\u003c\/td\u003e\n\u003ctd\u003eNumber of pieces\u003c\/td\u003e\n\u003ctd\u003e60 pcs\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eParametry\u003c\/td\u003e\n\u003ctd\u003eBasic ingredient\u003c\/td\u003e\n\u003ctd\u003efolic acid\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eParametry\u003c\/td\u003e\n\u003ctd\u003eProduct weight with unit packaging\u003c\/td\u003e\n\u003ctd\u003e0.04 kg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eParametry\u003c\/td\u003e\n\u003ctd\u003eEAN (GTIN)\u003c\/td\u003e\n\u003ctd\u003e5903242583186\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eParametry\u003c\/td\u003e\n\u003ctd\u003ePackaging status\u003c\/td\u003e\n\u003ctd\u003eoriginal\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eParametry\u003c\/td\u003e\n\u003ctd\u003eAdditional features\u003c\/td\u003e\n\u003ctd\u003egluten-free,lactose-free,safe for pregnant women,pure (without additives),vegan,vegetarian\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e","brand":"Biodly","offers":[{"title":"Default Title","offer_id":45771016994876,"sku":"16278913245","price":25.42,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0618\/2161\/6188\/files\/Aliness-Prenacare-FOLIAN-800g-Folic-acid-60tab-PREGNANCY-For-pregnant-women.jpg?v=1783119375","url":"https:\/\/market365.lt\/products\/maisto-papildas-nesciosioms-aliness-prenacare-folian-800-g-folio-rugsties-60-tableciu","provider":"Market365","version":"1.0","type":"link"}