{"product_id":"l-karnitinas-1000-mg-90-kapsuliu","title":"L-karnitinas 1000 mg, 90 kapsulių","description":"\u003ch2\u003eTrumpai apie prekę\u003c\/h2\u003e\u003cp\u003ePrekė: L-karnitinas 1000 mg, 90 kapsulių. Kategorija: Aminorūgštys.\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eGamintojas:\u003c\/strong\u003e Essensey\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eModelis:\u003c\/strong\u003e g43Eg3444\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSvoris:\u003c\/strong\u003e 57 g\u003c\/li\u003e\n\u003c\/ul\u003e \u003cul\u003e \u003cli\u003e\u003cb\u003eL-CARNITINE FROM THE ESSENCE BRAND, WHICH IS BECOMING MORE AND MORE POPULAR\u003c\/b\u003e\u003c\/li\u003e \u003cli\u003e\u003cb\u003eEXCELLENT PRODUCT DESIGNED FOR DEMANDING ATHLETES\u003c\/b\u003e\u003c\/li\u003e \u003cli\u003e\u003cb\u003eDAILY PORTION IS UP TO 1000 MG OF L-CARNITINE TARTRATE\u003c\/b\u003e\u003c\/li\u003e \u003cli\u003e\u003cb\u003eL-CARNITINE PLAYS AN IMPORTANT ROLE IN FAT METABOLISM\u003c\/b\u003e\u003c\/li\u003e \u003cli\u003e\u003cb\u003eL-CARNITINE IS INVOLVED IN THE TRANSPORT OF FATTY ACIDS TO THE MITOCHONDRIA OF THE CELL\u003c\/b\u003e\u003c\/li\u003e \u003cli\u003e\u003cb\u003eCOMFORT OF SUPPLEMENTATION, CONVENIENT FORM OF CAPSULES\u003c\/b\u003e\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003e\u003cb\u003eEssensey L-carnitine.\u003c\/b\u003e Dietary supplement in the form of capsules containing 1000 mg of L-carnitine tartrate in a portion of the product recommended for consumption during the day.\u003c\/p\u003e \u003ch2\u003eWhat is L-Carnitine?\u003c\/h2\u003e \u003cp\u003eL-carnitine is an endogenous compound synthesized in mammals from essential amino acids lysine and methionine. It is stored mainly in skeletal muscle and heart (about 95%), while much lower concentrations are stored in blood plasma (1). L-carnitine is of interest because it plays an important role in fat metabolism. The primary function of L-carnitine is to transport long-chain fatty acids through the inner membrane of the mitochondria. Due to its functions in the body, it also indirectly has an effect on carbohydrate metabolism (2).\u003c\/p\u003e\u003ch2\u003eNutritional Value \/ Nutritional Information: For 2 caps.\u003c\/h2\u003e \u003cul\u003e \u003cli\u003e\n\u003cb\u003eL-carnitine tartrate:\u003c\/b\u003e 1000 mg\u003c\/li\u003e \u003cli\u003e\n\u003cb\u003eincluding L-carnitine:\u003c\/b\u003e 680 mg\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003e\u003cb\u003eIngredients:\u003c\/b\u003e L-carnitine tartrate (78,1%), capsule shell (glazing agent - hydroxypropylcellulose), anti-caking agent (magnesium salts of fatty acids.\u003c\/p\u003e \u003cp\u003e* - Tartrazine can have a negative effect on activity and attention in children.\u003c\/p\u003e \u003cp\u003eMay contain unintended presence of milk derivatives, soybeans, cereals containing gluten, eggs, peanuts and other nuts.\u003c\/p\u003e \u003ch2\u003eRecommended intake \/ method of preparation:\u003c\/h2\u003e \u003cp\u003eTake 2 capsules a day, without chewing, with a sufficient amount of liquid, preferably 30 minutes before a meal or workout.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eDietary supplement.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eIt cannot be used as a substitute or substitute for a varied diet. Do not exceed the recommended daily intake. The product should not be administered to nursing mothers or pregnant women. Keep out of the reach of small children. Store in a dry place at room temperature up to 25°C. Protect from light.\u003c\/p\u003e \u003ch2\u003eL-carnitine is known among people who care about form!\u003c\/h2\u003e \u003cp\u003eThe mechanism of action of L-carnitine is not as simple as is commonly believed. According to the scientific publication on prolonged supplementation of L-carnitine for metabolism from 2020 (Sawicka et al. ), the main function of L-carnitine is to transport long-chain fatty acids to the mitochondrial matrix in order to convert them into energy in the beta-oxidation process. In addition, L-carnitine, through its reaction with acetyl-CoA (i.e. acetylcoenzyme A) and maintenance of the acetyl-CoA\/CoA ratio in the cell, regulates the activity of pyruvate dehydrogenase. L-carnitine also plays an important role in the regulation of metabolic pathways associated with skeletal muscle protein balance: proteolysis and protein synthesis (3) and acts as an antioxidant compound, thus it can alleviate exercise-induced muscle damage (4).\u003c\/p\u003e \u003ch2\u003ePopularity of L-Carnitine\u003c\/h2\u003e \u003cp\u003eL-carnitine is known and used by athletes around the world. It is recommended for active people looking for support in pursuing their goals. Of course, the basis for success is a refined diet and a well-thought-out training system – it is worth remembering. The form of capsules guarantees the comfort of supplementation.\u003c\/p\u003e \u003ch2\u003eSupplementation with L-carnitine\u003c\/h2\u003e \u003cp\u003eIn the aforementioned scientific publication (Sawicka et al. ), the authors concluded that supplementation with L-carnitine under certain conditions may affect physical performance. They also pointed out that, according to available studies, long-term supplementation, especially in combination with carbohydrates, may increase the total carnitine content in skeletal muscle (3).\u003c\/p\u003e \u003ch2\u003eL-carnitine and fatigue during exercise\u003c\/h2\u003e \u003cp\u003eFrom a physiological point of view, L-carnitine serves as a substrate, e.g. for the synthesis of acetylcarnitine, which is necessary to maintain a real pool of free coenzyme A (CoA). It enables the continuation of the pyruvate dehydrogenase complex – theoretically, it can be expected that its higher flow during strenuous exercise will reduce the accumulation of lactate in the blood. As a result, this will potentially help preserve glycogen stores and then delay premature fatigue (1).\u003c\/p\u003e \u003cp\u003e\u003cb\u003eEssence L-Carnitine – a great complement to intense workouts!\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003eLiterature:\u003c\/b\u003e\u003c\/p\u003e \u003col\u003e \u003cli\u003eKoozehchian M. S., Daneshfar A., Fallah E., Agha-Alinejad H., Samadi M., Kaviani M., Kaveh B. M., Jung Y. P., Sablouei M. H., Moradi N., Earnest C. P., Chandler L. J., Kreider R. B. Journal of Exercise Nutrition \u0026amp; Biochemistry, 2018, Dec 31;22(4):7-19.\u003c\/li\u003e \u003cli\u003eJeukendrup A. E., Randell R. Fat burners: nutrition supplements that increase fat metabolism. Obesity Reviews, 2011 Oct;12(10):841-51.\u003c\/li\u003e \u003cli\u003eSawicka A. K., Renzi G., Olek R. A., The bright and the dark sides of L-carnitine supplementation: a systematic review, Journal of the International Society of Sports Nutrition, 2020, 17, 49.\u003c\/li\u003e \u003cli\u003eBloomer R. J., Smith W. 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